Case Studies Archives - TCG Digital https://www.tcgdigital.com/category/case-studies/ Accelerating Digital Transformation with Enterprise AI Tue, 09 Sep 2025 06:36:13 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.1 https://www.tcgdigital.com/wp-content/uploads/2025/03/logo-mark.png Case Studies Archives - TCG Digital https://www.tcgdigital.com/category/case-studies/ 32 32 Transforming Bioanalytics with AI solutions for a Global Biotechnology Leader https://www.tcgdigital.com/transforming-bioanalytics-with-ai-solutions-for-a-global-biotechnology-leader/ Thu, 04 Sep 2025 12:30:03 +0000 https://www.tcgdigital.com/?p=3094 Transforming Bioanalytics with AI solutions for a Global Biotechnology Leader. – Powered by mcube™ Reduced rework cost Decreased errors Enhanced compliance  Overview […]

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Transforming Bioanalytics with AI solutions for a Global Biotechnology Leader. – Powered by mcube™

Reduced
rework cost

Decreased
errors

Enhanced
compliance 

Overview

A leading international biotechnology company sought to streamline its operations and accelerate the delivery of new therapies by digitizing and integrating workflows. The company’s bioanalytics processes, which are critical to its drug development lifecycle, previously consisted of manual workflows involving data transfers between systems. For which, company required AI integration to enhance efficiency, improve accuracy, and accelerate validation. This positioned the company to bring therapies to market more swiftly, reinforcing its commitment to innovation and excellence in drug development.

mcube™ Solutions

Direct analysis from your LIMS,  eliminates risk of data manipulation

Modular design with API connectors to various systems ensures flexibility and scalability

Unified platform for assay analytics across ADA, PK, Method Validation and ICH M10 compliant reporting

Solution that provides ICH M10 and CFR part 11 adherence  

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Transforming R&D/ Drug Discovery with AI solutions for a Global Biopharmaceutical Leader https://www.tcgdigital.com/transforming-rd-drug-discovery-with-ai-solutions-for-a-global-biopharmaceutical-leader/ Thu, 04 Sep 2025 11:53:56 +0000 https://www.tcgdigital.com/?p=3054 Transforming R&D/ Drug Discovery with AI solutions for a Global Biopharmaceutical Leader. Powered by mcube™ Cost saving Enhanced efficiency Improved data accuracy Comprehensive analysis […]

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Transforming R&D/ Drug Discovery with AI solutions for a Global Biopharmaceutical Leader.
Powered by mcube™

Cost saving

Enhanced efficiency

Improved data accuracy

Comprehensive analysis

Expected annual savings

$1.3

million for PK Assay Analysis

$0.8

million PK Assay Analysis with multiplex

$0.5

million Genotyping & Gene Expression Analysis 

Overview

To accelerate its mission of delivering life-saving treatments faster, a leading biopharma company set out to modernize its pharmacokinetics (PK), genotyping, and gene expression workflows. Faced with manual processes, fragmented systems, and compliance hurdles, the organization needed an integrated, AI-powered solution to streamline operations, ensure regulatory compliance, and support high-throughput R&D. By digitizing and unifying its bioanalytical workflows, the company is looking forward to drive efficiency, accuracy, and speed across assay analytics and genetic analysis. This transformation reflects its unwavering commitment to innovation and operational excellence throughout the drug development lifecycle.

Streamlines assay workflows with direct analysis from your LIMS.

Modular design with API connectors to various systems ensures flexibility and scalability.

Unified platform for assay analytics across ADA, PK, Genotyping, and Gene Expression.

Compliance-ready architecture ensures regulatory adherence.

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Optimizing Biopharmaceutical Manufacturing with AI https://www.tcgdigital.com/optimizing-biopharmaceutical-manufacturing-with-ai/ Thu, 07 Aug 2025 08:53:08 +0000 https://www.tcgdigital.com/?p=2921 Case StudyOptimizing Biopharmaceutical Manufacturing with AI A Case Study on ADMAlytics™powered by mcube™ Abstract This paper discusses the transformative impact of ADMAlytics™, […]

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Case Study
Optimizing Biopharmaceutical Manufacturing with AI

A Case Study on ADMAlytics™
powered by mcube™

Abstract

This paper discusses the transformative impact of ADMAlytics™, an AI-driven platform powered by mcube™, on the biopharmaceutical manufacturing processes at ADMA Biologics. It highlights the journey towards operational excellence through innovative implementations of an enterprise data lake with advanced analytics solutions, focusing on plasma pool efficiency and improvements, donor and plasma inventory management, yield prediction, manufacturing KPI monitoring, and application of Generative AI for enterprise search. The superior outcomes underscore significant advancements in production efficiency, data accessibility, and real-time decision-making processes.

Background

The necessity for innovation and efficiency in the biopharmaceutical industry is unprecedented, in light of unique challenges in manufacturing processes and regulatory demands. ADMA Biologics, in response, has engaged TCG Digital to leverage the mcube™ platform, aiming to revolutionize its manufacturing processes. This collaboration focuses on creating a data-driven decision-making ecosystem, addressing critical operational challenges, automating manual processes, and fostering a culture of continuous improvement and innovation.

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From Predicting the Champion to Powering the Game https://www.tcgdigital.com/from-predicting-the-champion-to-powering-the-game/ Wed, 07 May 2025 12:44:41 +0000 https://www.tcgdigital.com/?p=2695 Case StudyFrom Predicting the Champion to Powering the Game How mcube™ transformed the DFB-Pokal Final 2025 into ashowcase of AI excellence Overview […]

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Case Study
From Predicting the Champion to Powering the Game

How mcube™ transformed the
DFB-Pokal Final 2025 into a
showcase of AI excellence

Overview

On 24th May 2025, the iconic Olympiastadion Berlin witnessed VfB Stuttgart triumph over Arminia Bielefeld with a 4–2 scoreline in the DFB-Pokal Final. But the true game-changer had already taken the field long before the opening whistle. mcube™, TCG Digital’s AI platform, not only predicted Stuttgart’s victory with striking accuracy but also delivered a full-spectrum AI solution across content generation, multilingual storytelling, and real-time broadcasting.

This case study captures how mcube™ proved its prowess as a predictive intelligence engine and an AI storyteller, marking a defining moment in the evolution of AI-powered sports intelligence.

Challenge

Sports content production is fragmented, reactive, and limited by post-event workflows. Predicting outcomes with accuracy remains a probabilistic gamble. Delivering customized, multilingual, real-time content for multiple platforms across geographies and formats? Even harder.

The challenge: Could AI lead from the front—not just to report the game, but to predict, curate, narrate, and distribute it in real time across borders and languages?

Solution

mcube™’s AI-Powered Matchday Framework

At the DFB Pokal Final 2025, mcube™ delivered an integrated AI solution across four mission-critical fronts:

Predictive Match Intelligence

  • Prediction Engine:
    Trained on 10+ years of German football data and 500+ fixtures
  • Model:
    Dual-regressor XGBoost using features like Elo ratings, recent form, goal averages, and tier differences. The model was trained to predict individual team scores, then the predicted scores were compared to assess winning probability.
  • Predicted Result:
    Predicted Stuttgart would win (Scoreline: 3 – 2)
  • Confidence:
    76.43% win probability
Model Accuracy
  • Recent Semi-final Validation Accuracy: 100%
  • Total Validation Accuracy: 74.82%
  • Timeframe: Data from the last 5 years of DFB-Pokal matches
  • Training Size: Over 500 past fixtures across Bundesliga 1, 2, 3 & Cup
The model incorporated momentum, matchups, and goal margins, not just raw results and arrived at VFB Stuttgart having the statistical edge with accuracy.

Actual Result: Stuttgart 4 – 2 Arminia — a near-perfect forecast.

Broadcast & Content Distribution at Scale

AI-delivered match feeds customized for India’s vast and multilingual broadcaster ecosystem:

  • Prasar Bharati Sports
  • Waves OTT
  • GXR OTT
  • Kerala Super League
  • TV9 Network

Automated delivery in the right format, bitrate, and language—across TV, OTT, and social media.

Multilingual AI Storytelling

  • 11 languages instantly generated post-match: English, Hindi, Tamil, Telugu, Bengali, and more.
  • Cultural localization and tone adaptation ensured every region received fan-centric, relatable narratives.

Real-Time Highlight & Moment Curation

  • Every 10 minutes, mcube™ used sentiment analysis + gameplay signals to push:
    1. Best match moments
    2. Goal packages
    3. Tactical turning points
  • Distributed seamlessly across YouTube, TV, and OTT—automatically.

Results & Impact

Match Prediction Accuracy
Stuttgart win predicted with 76.43% confidence. Predicted score (3–2), Actual score (4–2).
AI Content Creation
11 localized reports generated instantly post-match.
Real-time Broadcasting
Streams tailored for 5+ broadcasters in India, fully automated.
Fan Engagement
Millions reached via YouTube & social media within minutes.
Validation
100% accuracy in semi-final predictions, 74.82% across DFB Pokal dataset.

Strategic Significance

The DFB-Pokal 2025 was not just a football match—it was a live demonstration of mcube’s potential to revolutionize the global sports ecosystem:

  • From predictive modeling to instant media delivery
  • From reactive coverage to proactive intelligence
  • From single-language reporting to multilingual, multi-platform storytelling

And this is just the beginning!

Conclusion

The DFB Pokal Final was more than just a prediction win. It was a proof-of-concept that AI like mcube™ can shape the entire lifecycle of a major sporting event—from predicting the outcome, curating the story, to broadcasting it in real time.

mcube™ is no longer just watching the game.
It’s powering it.

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AI-Powered Conversion Optimization for a Leading EU Downstream Operator https://www.tcgdigital.com/case-study-ai-powered-conversion-optimization/ Fri, 11 Apr 2025 05:14:45 +0000 https://tcgdigital.com/?p=1684 AI-Powered Conversion Optimization for a Leading European Downstream Operator ~2%​ increase in Conversion EfficiencyEnhanced operational stability resulting in higher throughputBetter catalyst management […]

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AI-Powered Conversion Optimization for a Leading European Downstream Operator

~2%​

increase in Conversion Efficiency
Enhanced operational stability resulting in higher throughput
Better catalyst management reducing waste

Business Challenge​

A major European downstream oil & gas operator sought to improve conversion efficiency and operational reliability within its LC-FINING unit, which processes heavy feedstock into lighter, high-value products. Despite sophisticated DCS systems and historical data, the plant faced difficulties in detecting early performance deviations due to variability in feed composition, catalyst fluctuations, and changing process dynamics. The lack of real-time correlation between key parameters—such as viscosity, reactor firing, and feed pump behavior—and the absence of a structured optimization approach limited their ability to consistently maximize yield and maintain process stability.

Solutions Deployed

  • A remote monitoring framework was deployed, enabling real-time visibility into process behavior flagging developing anomalies, recommending corrective actions ahead of time.
  • ML-Based Conversion Optimization Engine – ML models were trained on DCS data, lab reports, and operating history to predict:
    • Short Heavy Fraction Tolerance (SHFT), Feed Operability Index, Conversion potential under multiple operating constraints (e.g., reactor exotherm, catalyst availability)
  • Real-Time Dashboard with live insights into:
    • Feed integrity and reactor behavior
    • Catalyst performance and SHFT trends
    • Optimization targets and operating recommendations
  • Correlated Alerting System – Instead of isolated alarms, alerts were configured based on the combined movement of multiple process KPIs, enabling faster identification of pattern-based anomalies.
  • What-If Simulation & Decision Support – During steady-state periods, the system proposed setpoint changes using real-time model outputs, allowing operators to take proactive decisions grounded in data and business logic.

Benefits

  • ~2% increase in conversion efficiency, driving significant bottom-line impact
  • Faster anomaly detection and resolution, reducing unplanned variability and interventions
  • Enhanced operational stability, resulting in consistent product quality and throughput
  • Better catalyst management, reducing waste and improving overall asset performance

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Transforming Plant Reliability with Gen-AI https://www.tcgdigital.com/case-study-transforming-plant-reliability-with-gen-ai/ Fri, 11 Apr 2025 05:09:43 +0000 https://tcgdigital.com/?p=1666 Transforming Plant Reliability with Gen-AI: A Blueprint for Intelligent Operations in Specialty Chemicals $5M Cost Savings 30% Earlier detection of reliability risks […]

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Transforming Plant Reliability with Gen-AI: A Blueprint for Intelligent Operations in Specialty Chemicals

$5M

Cost Savings

30%

Earlier detection of reliability risks through multi-KPI anomaly correlation

Business Challenge​

Despite having advanced monitoring systems in place, the client—a global specialty chemicals leader—struggled with a persistent gap between data visibility and decision-making clarity. While their plants tracked production and equipment KPIs in real time, the insights were often generic, isolated, and lacked the context needed for timely intervention.

 

Operators were aware of abnormal readings, but lacked contextual guidance on what those deviations meant, how urgent they were, or whether they warranted intervention. The challenge became even more pronounced in situations where multiple KPIs were trending within acceptable limits, but collectively indicated a brewing anomaly. There was no clear visibility on the direct connection between these early warning signs and the financial impact of ignoring them — whether in lost production, equipment damage, or opportunity cost — issues often went unaddressed until they escalated into costly failures. The client needed a solution that could not only detect complex anomalies earlier, but also overlay them with financial and historical relevance to drive the right response, at the right time.

Solutions Deployed

  • Focused monitoring on assets most associated with production loss or reliability risk
  • Historical performance + SAP-PMS job orders and repair data augmented with OEM best practices for more holistic decision-making
  • GenAI-Powered Digital Process Advisor to provide contextualized fault trees and nudges to operators
  • Multi-Variable Correlation & Pattern-Based Anomaly Detection rather than isolated threshold breaches
  • Smart Alerting System and Remote Monitoring Dashboard for unified view of real-time plant behavior
  • ML based Stability & Reliability Index quantifying combined effect of anomalies on process and equipment health
  • Reinforcement Learning Loop to fine-tune recommendations and continuously improve the system’s intelligence

Benefits

Up to $5M in potential annual value through production loss avoidance, energy efficiency, and smarter maintenance

  • 30% earlier detection of reliability risks through multi-KPI anomaly correlation
  • 40% faster resolution time enabled by Gen-AI-guided fault trees and operator nudges
  • Reduction in maintenance cost overruns, by prioritizing financially significant issues

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Performance Digital Twin for leading Integrated Petrochemical Manufacturer https://www.tcgdigital.com/case-study-performance-digital-twin/ Fri, 11 Apr 2025 05:03:08 +0000 https://tcgdigital.com/?p=1665 Enhancing Plant Performance at Scale Using Digital Twin for a leading Integrated Petrochemical Manufacturer, AsiaIncreased yield and production Enhanced uptime of equipment […]

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Enhancing Plant Performance at Scale Using Digital Twin for a leading Integrated Petrochemical Manufacturer, Asia
Increased yield and production
Enhanced uptime of equipment and plant assets
Reduced energy consumption

Annual cost savings

Business Challenge​

To remain ahead in a highly competitive and efficiency-driven market, the leadership aimed to elevate digital maturity—moving beyond basic data collection to intelligent, real-time performance monitoring and optimization. The key challenge was to transform fragmented, under-leveraged data into dynamic intelligence that could drive real-time performance orchestration, increase yield, enhance energy efficiency, and increase asset reliability, while setting the stage for autonomous decision-making and future-ready operations.

Solutions Deployed

We deployed a digital twin solution powered by mcube, to transform plant monitoring from reactive to intelligent and insight-driven.

Key initiatives included:
  • Building a digital replica of the plant, integrated with a real-time data lake capturing sensor and process data.
  • Enabling real-time monitoring of plant health, KPI’s, and equipment conditions.
  • Implementing detailed visibility across all major systems—feedstock, cracking, polymerization, storage, and utilities.
  • Empowering teams with visual dashboards, performance baselines, alerts, and root cause diagnostics.

Benefits

$8M in projected savings/revenue augmentation driven by:

  • Increased production and improved yield
  • Reduced energy consumption
  • Enhanced uptime of equipment and plant assets
  • Faster issue detection and response

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Automatic load distribution and load control for steel producer, Netherlands https://www.tcgdigital.com/case-study-european-steel-producer/ Fri, 11 Apr 2025 04:51:34 +0000 https://tcgdigital.com/?p=1655 Automatic load distribution and load control for steel producer, Netherlands 80% Reduction in Venting 5% Energy saving Significant Reduction of Operator Workload […]

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Automatic load distribution and load control for steel producer, Netherlands

80%

Reduction in Venting

5%

Energy saving

Significant

Reduction of Operator Workload

Annual cost savings

Business Challenge​

The plant operators were facing  plant insufficiencies such as 10% product blow off (average), inefficient load distribution across five production plants creating high production cost. Furthermore, fast demand changes in the complex network created stress at plant operators and frequent start/stop of plants and compressors increased risk and reduced asset lifetime.

Solutions Deployed

Real-time Optimizer (RTO)
  • Production continuously optimized by RTO
  • Gas network optimization controlling load of three O2 production plants (ASU) in real-time
  • Elimination of venting, optimized efficiency and improved reliability

Benefits

  • 80% reduction in venting , significantly increasing plant efficiency.
  • 5% energy saving, significantly improving the CO2 footprint of plants.
  • Significant reduction of operator workload, effectively reducing stress and improving wellbeing of plant operators.
These improvements collectively delivered an annual savings of 1M USD.

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Case Study US Based Ethylene Production Plant https://www.tcgdigital.com/case-study-us-based-ethylene-production-plant/ Fri, 11 Apr 2025 04:46:03 +0000 https://tcgdigital.com/?p=1645 Real-time analytics & Advanced Automation for Cracker, Texas US 1.7% Increase in Ethylene Production (kt/y) 52% Increase in furnace run-length (d/run) 46% […]

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Real-time analytics & Advanced Automation for Cracker, Texas US

1.7%

Increase in Ethylene Production (kt/y)

52%

Increase in furnace run-length (d/run)

46%

Reduction in Decoking time (h/y)

Annual cost savings

Business Challenge​

In response to rising global competition in the steel industry, plant management initiated efforts to optimize operations, focusing on enhancing productivity and maximizing product yield.

Solutions Deployed

Real-time Advisor & Furnace Coil Monitor
  • Optimized plant reliability, profitability and performance
  • Maximized furnace run-length and avoidance of coil overheating

Benefits

  • 1.7% increase in ethylene production significantly increasing plant productivity.
  • 52% increase in furnace run-length, significantly reducing OPEX.
  • 46% reduction in decoking time, significantly increasing efficiency.
Collectively delivering annual savings of 7.8M USD.

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Advanced Automation for Leading Semiconductor Fab, Oregon US​ https://www.tcgdigital.com/case-study-large-semiconductor-lab/ Fri, 11 Apr 2025 04:36:28 +0000 https://tcgdigital.com/?p=1635 Advanced Automation forLeading Semiconductor Fab, Oregon US​ 40% Reduction in power consumption 30% Reduction of GAN blow off 25% Reduction inPlant start-up […]

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Advanced Automation for
Leading Semiconductor Fab, Oregon US​

40%

Reduction in power consumption

30%

Reduction of GAN blow off

25%

Reduction in
Plant start-up time 

Annual cost savings

Business Challenge

Operators struggled to consistently achieve ultra-high purity levels (10 ppb) required for semiconductor-grade products. Due to concerns over potential purity loss, they were reluctant to adjust ASU loads, especially during fluctuating demand. This led to frequent product venting and yield loss, as manual control lacked the precision and confidence needed for real-time optimization

Solutions Deployed

Automatic Sequence Transition

  • Automatic “one-button” ASU start-up from cold condition
  • Automatic transition between single & dual main air compressor mode

Linear Model Predictive Control

  • Optimization of efficiency & change plant load

Benefits

  • 40% reduction in power consumption, significantly lowering operational costs.
  • 30% decrease in GAN blow-off, enhancing product yield and process efficiency.
  • 25% faster Plant start-up,  improving responsiveness.
These improvements collectively delivered an annual savings of $2.5M USD.

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